Mayo Clinic

GSI is One of Ten Practices Selected for Mayo Clinic Trial.

Gastroenterology of Southern Indiana is one of ten practices in the entire country selected to participate in a trial being conducted by the prestigious Mayo Clinic in an effort to prevent colorectal cancer.


The Endoscopic Quality Improvement Project (EQUIP) focuses on the adenoma detection rate (ADR), which measures the percentage of colonoscopy patients in whom adenomas (or polyps) are detected. A higher ADR suggests a higher degree of accuracy in detecting and removing polyps in the colon, particularly those which are harder to detect and which have the potential to become cancerous, such as flat or serrated polyps.


A number of studies, including one funded by the Kaiser Permanente Community Benefit program and the National Cancer Institute, published this month in the New England Journal of Medicine, have found that higher ADRs result in fewer deaths from colorectal cancer. The NEJM study concluded, “The adenoma detection rate was inversely associated with the risks of interval colorectal cancer, advanced-stage interval cancer, and fatal interval cancer.”


The first part of the trial was conducted at the Mayo Clinic. The national trial will involve ten practices selected by the Mayo Clinic for excellence in this area. Gastroenterology of Southern Indiana was the first practice selected for the trial.


According to Dr. Michael B. Wallace of the Mayo Clinic, who serves as Principal Investigator for the project, the first step is to establish a baseline by identifying current ADR levels for each of the participants. Five of the ten will take part in additional training presented by Mayo Clinic medical staff. The ten practices will then be monitored to determine the impact of the additional training and education on ADRs. The control group will also receive training and education at the conclusion of the trial.


According to Dr. Wallace, “The baseline level of quality at Gastroenterology of Southern Indiana is extremely high. It will be challenging to improve their level, because it’s already so high.” He went on to say that the national ADR average is 20%. The ADR for Gastroenterology is 47%, “more than twice the national average, and the same as the ADR at the Mayo Clinic,” noted Dr. Wallace.


According to Dr. Stuart Coleman of GSI, that higher ADR is the result of a great deal of effort and a focused approach to care. “For example, when we perform a procedure,” he explained, “we have a lot of eyes on the screen: the physician, the nurse, the tech. Working as a team, we have a better chance of identifying those hard-to-detect polyps that might escape the notice of just one pair of eyes.”


Gastroenterology of Southern Indiana was founded in 1985 with a vision of providing superior care and expertise to Kentuckiana patients with medical issues related to the health and function of the digestive system. In the years since, the practice has grown as the need for such services has increased, staying at the forefront of medical knowledge in this important field, and investing in technology that allows them to continually improve and enhance the care they provide.


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